Panjin Jiahe Shengshi Medical Technology Co., Ltd
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Polyhexamethylene diguanide hydrochloride solution

Polyhexamethylene diguanide hydrochloride solution



Chemical Name

N,N-1,6-hexanediylbis[N-cyano-, polymer with1,6-hexanediamine, hydrochloride; 1,6-Hexanediamine, polymer with N,N-16-hexanediylbis{N-cyanoguanidine},hydrochloride

Molecular Formula



【Appearance】Colorless or faint yellow and clear liquid; viscosity: 5-6cP; pH: 4.0-6.0; specific gravity: 1.04g/ml; boiling point: 102℃; miscible with water. 【Active content】19%~21%. Mode and mechanism of action: guanidine group of PHMB is highly active to make the polymer positively charged so that it is easy to be absorbed by various bacteria and virus and inhibit the division of bacteria and virus to deprive their proliferation ability. In addition, the thin film formed by the polymer can congest the respiratory passage of the micro-organisms to suffocate them to death rapidly. Another active ingredient of PHMB hydrochloric acid can enhance its microbicidal efficacy. Advantages of PHMB: 1. Rapid microbicidal effect; 2. Broad-spectrum bactericidal effect at a low dosage; 3. High efficacy in hard and soft water; 4. Tolerance to organic materials, e.g. proteins, lipids and blood; 5. Surface streak or adhesiveness would not be caused; 6. Stable and effective under a broad range of pH (1-11); 7. Low foam, suitable for piping systems of CIP system and pasteurization; 9. No growth of identified body resistance; 10. Easy to rinse without residuals; 11. Safe for demanding instruments without corrosion. 12. Buffer effect, tolerant to at least 50 times of washing in textile. Application: Polyhexamethylene biguanidine hydrochloride (PHMB), a new guanidine disinfectant, is more broad-spectrum, safer and more effective compared with existing chlorhexidine and PHMG (polyhexamethylene monoguanidine). PHMB can be extensively used in cosmetics industry, water disposal and area of health. It is usually applied in women’s lotion, disinfectants and preservatives in wipes, sanitizers for aquatic products and flocculation disinfectants for sewage disposal. Bacteriostatic effect for Bacillus subtilis, Saccharomyces cerevisiae and Aspergillus niger of PHMB is superior to that of PHMG. Killing effects for micro-organisms and virus: Micro-organisms PHMB20% (PPM) Virus PHMB20% (PPM) Bacillus subtilis 1.5 HongKong influenza virus 300 Enterobacter cloacae 40 HSV-1 300 Escherichia Coli 0157: H7 80 vaccinia virus 300 legionella pneumophilia 5 rotavirus 200 Listeria monocytogenes 30 avian infectious laryngotracheitis virus 20 proteusbacillus vulgaris 40 Bovine herpesvirus 20 Pseudomonas aeruginosa 40 fowlpox virus 80 Pseudomonas putida 25 transmissible gastroenteritis virus of swine 80 Salmonella choleraesuis 120 foot and mouth disease virus 2000 Salmonella typhimurium 160 Feline infectious peritonitis virus 400 Staphylococcus aureus 30 feline influenza virus 200 Streptococcus faecium 5 Canine parvovirus 400 Lactic streptococci 20 saccharomycetes PHMB20% (PPM) amoeba PHMB20% (PPM) Candida albicans 300 Acanthamoeba virus 5 Saccharomyces rubrum 7.5 Saccharomyces cerevisiae 300 Influential factors of microbicidal effect: With the increase of the concentration, temperature and action time, the microbicidal effect of PHMB will be enhanced. pH value of 2-11 has little impact on the microbicidal effect, when pH value is higher, the microbicidal effect strengthens a little bit. Organic matters have little impact on its microbicidal effect. 【Property】This product has a wide microbicidal spectrum without resistance; has a low effective concentration, rapid action, stable property, it is miscible with water and can be used under ambient temperature; has long-term bacteriostatic effect without side effects, corrosion and bleachability; clear, colorless, odorless, non-toxic and nonirritant; non-ignitable and non-explosive, safe to use. 【Standard】National standard GB-26367-2010. 【Storage】Keep tightly closed in a cool and dry place, protect from light. 【Shelf life】2 years. [Packing specification] 25kg/barrel.